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Power ON is an NSF for Sport Certified supplement that uses a proprietary synergistic blend of 15 ingredients that have been studied in humans to improve mental performance.
Power ON contains a full clinical dose of COGNIZIN, orm of citicoline that provides vital nutrients that help the brain stimulate electronic impulses, generate energy in the brain (adenosine triphosphate), maintain healthy neurons and protect them from free radicals.
One of the ingredients in Alpha Brain is Vinpocentine.
As of September 2016, Vinpocetine is an ingredient that the FDA does not consider to be a dietary ingredient and is instead a synthetic compound. Click here to read the FDA's official notice.
Vinpocetine is prescribed as a drug in Germany, China, and Russia for acute stroke and cognitive impairment.1, 2
Because Vinpocetine is a not an approved substance, manufacturing practices tend to be unreliable. One study of 23 supplement products containing Vinpocetine from major supplement retailers found either no Vinopectine in some samples, and doses ranging from 0.3mg to 32mg.3
The US National Toxicology Program has also published a review of Vinpocetine citing adverse reactions in the studies it references including: nausea, dizziness, dry mouth, transient hypo- and hyper-tension, headaches, heartburn, and changes in blood pressure and blood glucose levels4
1. D.Bereczki, I.Fekete. Vinpocetine for acute ischaemic stroke. Cochrane Database of Systematic Reviews 2008, Issue 1. Art. No.: CD000480.
2. D. Bereczki, I. Fekete. A systematic review of vinpocetine therapy in acute ischaemic stroke. Eur. J. Clin. Pharmacol. 1999, 55, 349.
3. Avula B, Chittiboyina A, Sagi S et al. Identification and quantification of vinpocetine and picamilon in dietary supplements sold in the United States. Drug Test Anal. 2015;8(3-4):334-343. doi:10.1002/dta.1853
4. National Toxicology Program. Chemical information review document for vinpocetine. CAS No. 42971-09-5, September 2013; Available at: http://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ vinpocetine091613_508.pdf